Machicado G A, Cheng S, Jensen D M
UCLA Center for the Health Sciences, USA.
Gastrointest Endosc. 1997 Feb;45(2):157-62. doi: 10.1016/s0016-5107(97)70240-2.
(1) to prospectively evaluate efficacy and safety of direct current (DC) probe treatment of chronic anal fissures associated with internal hemorrhoids, and (2) to estimate direct and indirect costs of anoscopic treatment versus surgery.
Ten patients with chronic fissures of 11 mm (mean length) had symptoms for 5 months (mean) in spite of medical management; all had internal hemorrhoidal disease. DC coagulation was applied to two or three contiguous internal hemorrhoids per outpatient session. Eleven mA (mean) of DC current was delivered for 7 minutes (mean) per hemorrhoid segment.
All 10 patients had relief of chronic anal pain within two treatments and nine anal fissures healed within 4 weeks. One patient developed a perianal abscess and fistula requiring surgery. There were no recurrences in 20 months (mean) of follow-up with medical management. Mean direct and indirect costs (in terms of lost time from work or usual activity) of DC probe treatments were estimated to be 10% to 30% lower and 2 to 10 times less, respectively, than standard surgery for chronic anal fissures.
DC probe treatment for chronic anal fissures associated with internal hemorrhoidal disease is an important advance as an effective, safe, and cost-effective nonsurgical treatment in selected patients.
(1)前瞻性评估直流电(DC)探头治疗伴有内痔的慢性肛裂的疗效和安全性,(2)估算肛门镜检查治疗与手术治疗的直接和间接成本。
10例慢性肛裂患者,肛裂平均长度为11毫米,尽管接受了药物治疗,但平均仍有5个月的症状;所有患者均患有内痔疾病。每次门诊对两到三个相邻内痔进行直流电凝固治疗。每个痔段平均施加11毫安直流电,持续7分钟。
所有10例患者在两次治疗内慢性肛门疼痛均得到缓解,9例肛裂在4周内愈合。1例患者出现肛周脓肿和肛瘘,需要手术治疗。在20个月(平均)的药物治疗随访中无复发。与慢性肛裂的标准手术相比,直流电探头治疗的平均直接和间接成本(以工作或日常活动的时间损失计算)分别估计低10%至30%和少2至10倍。
对于伴有内痔疾病的慢性肛裂,直流电探头治疗作为一种有效、安全且具有成本效益的非手术治疗方法,是一项重要进展。