Komolova G S, Guseĭnova F T, Makeeva V F, Egorov I A, Tigranian R A
Kosm Biol Aviakosm Med. 1977 Jul-Aug;11(4):17-9.
The effect of space flight on the content of nucleic acids and the structure of DNA in the rat liver and spleen was studied. The 22-day exposure did not influence the DNA content in tissues, whereas the RNA content decreased by 14% and 19% in the liver and spleen, respectively. The flight did not induce changes like one-stranded or paired breakages in the DNA structure. Studies of the liver showed a minor trend towards a fall of elastic viscosity of the DNA supermolecular structure (difference between the flight and control rats was statistically insignificant). The above changes in the state of nucleic acids in the liver and spleen were transient.
研究了太空飞行对大鼠肝脏和脾脏中核酸含量及DNA结构的影响。22天的暴露并未影响组织中的DNA含量，而肝脏和脾脏中的RNA含量分别下降了14%和19%。飞行并未诱导DNA结构出现单链或双链断裂等变化。对肝脏的研究显示，DNA超分子结构的弹性粘度有轻微下降趋势（飞行大鼠与对照大鼠之间的差异无统计学意义）。肝脏和脾脏中核酸状态的上述变化是短暂的。
