Jensen M B, Hessov I
Surgical Department L, Aarhus Amtssygehus, University Hospital of Aarhus, Denmark.
Br J Surg. 1997 Jan;84(1):113-8.
Postoperative fatigue and deterioration in functional capacity have been correlated to postoperative weight loss. This suggested that nutritional support to enhance the regain of weight might improve upon the convalescence.
Patients were allocated randomly at discharge to standard management or to dietary advice and protein-rich supplements for 4 months. The convalescence of 32 patients admitted electively for colorectal surgery and of 21 operated on for acute obstruction or severe peritonitis was studied.
The intervention substantially increased protein intake, gain in body-weight and lean body mass, especially in the legs as shown by dual-energy X-ray absorptiometry. Changes in work capacity, hand grip and pinching strength, fatigue and quality of life were similar in patients in control and intervention groups and had returned to preoperative values 1-2 months after operation, although fatigue was increased at 2-3 months.
This study did not support the hypothesis that changes in weight were important for the changes in function and fatigue in patients with small to moderate weight loss.
术后疲劳及功能能力下降与术后体重减轻相关。这表明提供营养支持以促进体重恢复可能会改善康复情况。
患者在出院时被随机分配至接受标准管理或接受饮食建议及富含蛋白质的补充剂，为期4个月。对32例择期接受结直肠手术的患者以及21例因急性肠梗阻或严重腹膜炎接受手术的患者的康复情况进行了研究。
干预措施显著增加了蛋白质摄入量、体重增加以及瘦体重，尤其是腿部的瘦体重，双能X线吸收法显示了这一点。对照组和干预组患者的工作能力、握力和捏力、疲劳及生活质量变化相似，术后1 - 2个月恢复到术前水平，尽管在术后2 - 3个月疲劳有所增加。
本研究不支持以下假设，即对于轻至中度体重减轻的患者，体重变化对功能和疲劳变化具有重要意义。
