Colberg J W, Andriole G L, Catalona W J
Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
Br J Urol. 1997 Jan;79(1):54-7. doi: 10.1046/j.1464-410x.1997.29912.x.
To determine the long-term outcome of men with carcinoma of the penis with clinically negative lymph nodes undergoing a modification of the standard inguinal lymphadenectomy.
The study included nine men (mean age 56.2 years, range 41-72) with squamous cell carcinoma of the penis who underwent a modified inguinal lymphadenectomy.
Of the nine patients, three had histologically positive lymph nodes; none of the patients with positive or negative nodes had evidence of recurrent disease. All patients were alive within a follow-up of 13-108 months (mean 67.5). Early post-operative complications occurred in two patients with skin-flap necrosis, one with prolonged lymphatic drainage and one with a delayed groin lymphocele and cellulitis.
The modified inguinal lymphadenectomy is a reasonable alternative to surveillance and may accurately identify men with positive nodes. Long-term survival and low morbidity seem to justify this approach in men with squamous cell carcinoma of the penis and clinically negative inguinal lymph nodes.
确定阴茎癌且临床腹股沟淋巴结阴性的男性患者接受改良标准腹股沟淋巴结清扫术后的长期预后。
该研究纳入了9名阴茎鳞状细胞癌男性患者(平均年龄56.2岁,范围41 - 72岁),他们接受了改良腹股沟淋巴结清扫术。
9名患者中,3名组织学检查显示淋巴结阳性;无论淋巴结阳性或阴性患者,均无疾病复发迹象。所有患者在13 - 108个月(平均67.5个月)的随访期内均存活。术后早期并发症发生在2例皮瓣坏死患者、1例淋巴引流延长患者以及1例腹股沟淋巴囊肿和蜂窝织炎延迟发生患者中。
改良腹股沟淋巴结清扫术是一种合理的监测替代方法,且可能准确识别淋巴结阳性患者。对于阴茎鳞状细胞癌且临床腹股沟淋巴结阴性的男性患者,长期生存和低发病率似乎证明了这种方法的合理性。