Pietak S, Holmes J, Matthews R, Petrasek A, Porter B
Department of Anaesthesia, Queen's University, Kingston, Ontario.
Can J Anaesth. 1997 Feb;44(2):198-201. doi: 10.1007/BF03013009.
Prosthetic revision of hip fractures may result in embolization of tissue products leading to death. In this report, from cases reported to the Anaesthesia Advisory Committee to the Chief Coroner of Ontario, emphasis is placed on the immediate resuscitative procedures which may offset a fatal outcome.
Two elderly patients are reported in whom hip fractures necessitated primary prosthetic hip repair. The first patient, with a history of limited cardiac reserve and syncope, suffered a subcapital hip fracture. Under general anaesthesia, a Moore's prosthesis was inserted. The anaesthetic period remained relatively stable until surgical reaming of the femoral canal. Bradycardia, hypotension and cyanosis developed and quickly proceeded to a fatal cardiac arrest. Autopsy demonstrated diffuse pulmonary embolism of fat and thrombus. The second patient suffered a fracture around the stem of a previously inserted femoral prosthesis. Under general anaesthesia, a new cemented hip prosthesis was inserted, following which hypotension occurred. This was supported with small doses of ephedrine, ventilation was controlled with oxygen and the procedure was quickly terminated. Despite addition of a dopamine infusion, cardiac arrest and death followed. Autopsy disclosed massive fat and bone marrow embolization.
The combination of hip fracture, activated clotting factors and borderline cardiopulmonary function presents a risk of death from embolization of tissue products released during the placement of a cemented hip prosthesis. While the outcome of this catastrophe is generally poor, all practitioners should be prepared to immediately institute resuscitative procedures to manage the accompanying cardiovascular collapse.
髋部骨折的假体翻修可能导致组织产物栓塞,进而导致死亡。在本报告中,根据向安大略省首席验尸官麻醉咨询委员会报告的病例,重点强调了可能抵消致命后果的即时复苏程序。
报告了两名老年患者,他们因髋部骨折需要进行初次人工髋关节修复。第一名患者有心脏储备功能受限和晕厥病史,发生了股骨头下骨折。在全身麻醉下,植入了一个穆尔假体。麻醉期相对稳定,直到对股骨髓腔进行手术扩髓。出现了心动过缓、低血压和发绀,并迅速发展为致命的心脏骤停。尸检显示有脂肪和血栓的弥漫性肺栓塞。第二名患者在先前植入的股骨假体柄周围发生骨折。在全身麻醉下,植入了一个新的骨水泥型髋关节假体,随后出现低血压。用小剂量麻黄碱进行支持,用氧气控制通气,手术迅速终止。尽管加用了多巴胺输注,仍发生心脏骤停并导致死亡。尸检发现大量脂肪和骨髓栓塞。
髋部骨折、活化凝血因子和临界心肺功能相结合,存在因骨水泥型髋关节假体植入过程中释放的组织产物栓塞而导致死亡的风险。虽然这场灾难的结局通常很差,但所有从业者都应准备好立即采取复苏程序来处理随之而来的心血管崩溃。