Applebaum E L, Clemis J D
Laryngoscope. 1977 Oct;87(10 Pt 1):1753-9. doi: 10.1288/00005537-197710000-00022.
A temporal bone report is presented of a patient with progressive sensorineural hearing loss and advanced Paget's disease involving the skull. The histopathology reveals Pagetic bone invading the internal auditory canal and compressing the cochlear division of the VIIIth cranial nerve resulting in severe neural degeneration. There are no other histopathologic abnormalities present in the cochlea to explain the hearing loss. A low-frequency conductive hearing loss was also present, but no histopathologic correlate could be identified.
本文报告了一例患有进行性感音神经性听力损失且颅骨受累于晚期佩吉特病的患者的颞骨情况。组织病理学显示，佩吉特骨侵入内耳道并压迫第八颅神经的耳蜗分支，导致严重的神经变性。耳蜗中不存在其他可解释听力损失的组织病理学异常。还存在低频传导性听力损失，但未发现与之相关的组织病理学特征。
