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[仔猪出生后早期发育阶段红细胞抗氧化系统酶的年龄相关变化]

[The age-related changes in the antioxidant system enzymes of the erythroid cells of swine at the early stages of postnatal development].

作者信息

Snityns'kyĭ V V, Antoniak H L, Bershads'kyĭ V I

出版信息

Fiziol Zh (1994). 1996;42(5-6):19-25.

PMID:9044806
Abstract

The age changes of energy metabolism and antioxidative system enzymes activity in "young", "mature" and "old" erythroid cells of 0-, 1-, 3-, 5-, 10-days old piglets were studied. The essential increase of superoxide dismutase and glutathione peroxidase activities in pig erythrocytes during three days of postnatal life was established. The rise of glucose-6-phosphate dehydrogenase and NADPH-dependent glutathione reductase activities was observed in piglets erythrocytes in the period from 5 to 10 days after birth. The discovered changes of enzymatic activity were particularly characteristic of the "young" cells. It is supposed that this mechanism is essential in erythrocyte membrane structures stabilization in the period of early postnatal adaptation of animals.

摘要

研究了0、1、3、5、10日龄仔猪“年轻”、“成熟”和“衰老”红细胞能量代谢及抗氧化系统酶活性的年龄变化。确定了出生后三天内猪红细胞中超氧化物歧化酶和谷胱甘肽过氧化物酶活性显著增加。在出生后5至10天期间,仔猪红细胞中葡萄糖-6-磷酸脱氢酶和NADPH依赖性谷胱甘肽还原酶活性升高。所发现的酶活性变化在“年轻”细胞中尤为明显。据推测,这一机制对于动物出生后早期适应期红细胞膜结构的稳定至关重要。

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