Shutov A M, Potrashkova K I, Prokaeva P A, Lesnikov I R
Ter Arkh. 1996;68(11):35-7.
Blood sera and concentrated urine were tested for antibodies to HFRS virus. 18 patients were in acute period and 16 had suffered from HFRS 16 years before. Indirect IFA test revealed antibodies in urine of 16 (88.9%) patients with HFRS. Urine antibodies disappeared for 9-22 days. There were no antibodies in the urine of patients with the history of HFRS, though it was registered in high titre in the blood serum. Thus, if the patient has antibodies to HFRS both in the blood and urine, it says about acute stage of the disease and can be used for earlier diagnosis of HFRS.
检测血清和浓缩尿中的汉坦病毒抗体。18例患者处于急性期,16例患者16年前曾患过汉坦病毒肾综合征出血热(HFRS)。间接免疫荧光抗体试验显示,16例(88.9%)HFRS患者尿中有抗体。尿抗体在9 - 22天内消失。有HFRS病史的患者尿中无抗体,尽管血清中抗体呈高滴度。因此,如果患者血液和尿液中均有HFRS抗体,则说明处于疾病急性期,可用于HFRS的早期诊断。