Sørensen M B, Weibull A S, Haubek A, Rokkjaer M, Jørgensen J
Arhus Universitetshospital, Arhus Kommunehospital, kirurgisk-gastroenterologisk afdeling L.
Ugeskr Laeger. 1997 Feb 3;159(6):743-7.
A retrospective study of 65 patients with postoperatively verified pancreatic or peripancreatic cancer was conducted. Before surgery all patients had ultrasonography (US) performed, and 46 patients had computed tomography (CT) performed as well. After operation description of pre-operative radiological findings has been compared to description of operative and pathological findings. Three of the 65 patients were excluded either because of lacking radiological descriptions (two patients) or uncertain operative findings (one patient). When both investigations were performed, they were carried out independently by two skilled radiologists without knowledge of the result of the other investigations. The following criteria were used for non-resectability encasement of splanchnic vessels, liver metastases, peritoneal thickening with ascites, and glandular enlargement. As assessed by US, 15 of 16 (94%) were truly predicted to be non-resectable, whereas only 21 of 38 (55%) were truly predicted resectable. CT was performed in 46 patients of which 19 of 21 (90%) were truly predicted non-resectable, and 17 of 21 (81%) were truly predicted resectable. It was not possible to perform a conclusive radiological investigation in eight of 62 (13%) cases by US, and four of 46 (9%) cases by CT. One patient was falsely predicted non-resectable by US and an additional one by CT. Both were falsely predicted non-resectable on suspicion of vessel involvement. Overall, invasion of vessels was the most common cause for non-resectability, at the same time this was the index of non-resectability that was most often not detected pre-operatively. US is reliable when predicting non-resectability. When resectable tumour is detected by US, supplementary investigations such as CT should be applied, and when necessary endoscopic procedures or laparoscopy as well. Hereby unnecessary laparotomies may be avoided. Care should be taken when suspecting papillary tumour; only 66% of these were detected by either of the two methods.
对65例术后经证实患有胰腺癌或胰腺周围癌的患者进行了一项回顾性研究。所有患者在手术前均接受了超声检查(US),其中46例患者还接受了计算机断层扫描(CT)。术后将术前影像学检查结果的描述与手术及病理检查结果的描述进行了比较。65例患者中有3例被排除,其中2例是因为缺乏影像学描述,1例是因为手术结果不确定。当两项检查都进行时,由两名经验丰富的放射科医生独立进行,且彼此不知道对方的检查结果。以下标准用于判断不可切除:内脏血管受包绕、肝转移、伴有腹水的腹膜增厚以及腺体增大。经超声评估,16例中有15例(94%)被准确预测为不可切除,而38例中只有21例(55%)被准确预测为可切除。46例患者进行了CT检查,其中21例中有19例(90%)被准确预测为不可切除,21例中有17例(81%)被准确预测为可切除。62例中有8例(13%)经超声检查无法得出确定性的影像学结论,46例中有4例(9%)经CT检查无法得出确定性的影像学结论。1例患者经超声检查被错误地预测为不可切除,另有1例经CT检查被错误地预测为不可切除。两者均因怀疑血管受累而被错误地预测为不可切除。总体而言,血管侵犯是不可切除的最常见原因,同时这也是术前最常未被检测到的不可切除指标。超声在预测不可切除性方面是可靠的。当超声检测到可切除肿瘤时,应进行补充检查,如CT,必要时还应进行内镜检查或腹腔镜检查。由此可以避免不必要的剖腹手术。怀疑为乳头状肿瘤时应谨慎;这两种方法中只有66%的此类肿瘤能被检测到。