Baĭborodov B D, Savel'eva T V, Prokopenko V M, Evsiukova I I, Arutiunian A V
Anesteziol Reanimatol. 1996 Nov-Dec(6):56-8.
Hyperbaric oxygenation (HBO) was added to the complex of intensive care for 14 full-term newborns born asphyxiated and with cerebral circulation disorders of the I-II degree. Study of the antioxidant enzymatic system and free-radical oxidation by chemiluminescence showed no changes in superoxide dismutase and catalase and a 1.6-2 times increase in the activity of glutathione peroxidase, on the one hand, and an appreciable decrease of free radical processes, on the other. This permitted a conclusion about the absence of toxic effects during HBO and on its membrane-stabilizing action.
对14例足月出生时窒息且伴有I-II度脑循环障碍的新生儿，在重症监护综合治疗中加入了高压氧治疗（HBO）。通过化学发光法对抗氧化酶系统和自由基氧化进行研究发现，一方面超氧化物歧化酶和过氧化氢酶没有变化，谷胱甘肽过氧化物酶活性增加了1.6 - 2倍，另一方面自由基过程明显减少。由此可以得出结论，高压氧治疗期间不存在毒性作用，且具有膜稳定作用。
