Schlierf G, Vogel G, Heuck C C, Oster P, Raetzer H, Schellenberg B
Monatsschr Kinderheilkd (1902). 1977 Aug;125(8):770-3.
The efficacy of a fat-modified, low-cholesterol diet was studied in 38 children and adolescents with familial hypercholesterolemia on an out-patient basis, and the results compared with those achieved with dietary treatment in hospital. On an out-patient basis, a 10% reduction of plasma cholesterol levels was achieved and maintained. However, no patient showed normalization of plasma cholesterol levels. During hospitalisation, the mean plasma cholesterol levels fell by 24%, beta-cholesterol levels by 27%. This resulted in normal plasma lipids in almost half of the patients. Our results demonstrate the efficacy of intensive dietary management in children and adolescents with familial hypercholesterolemia. Long-term results on an out-patient basis could probably be improved by early nutrition education and an improved supply of suitable dietary foods.
对38名患有家族性高胆固醇血症的儿童和青少年进行了门诊脂肪改良、低胆固醇饮食疗效研究，并将结果与住院饮食治疗的结果进行比较。在门诊治疗中，血浆胆固醇水平降低了10%并得以维持。然而，没有患者的血浆胆固醇水平恢复正常。住院期间，平均血浆胆固醇水平下降了24%，β-胆固醇水平下降了27%。这使得近一半的患者血脂恢复正常。我们的结果证明了强化饮食管理对患有家族性高胆固醇血症的儿童和青少年的疗效。通过早期营养教育和改善合适饮食食物的供应，门诊治疗的长期效果可能会得到改善。
