Yaffe H, Eldor A, Hornshtein E, Sadovsky E
Obstet Gynecol. 1977 Oct;50(4):454-6.
Thromboplastic activity of amniotic fluid (TAAF) was determined in 97 normal and pathologic pregnancies using a modification of Quick's one-stage method for prothrombin time. It was shown that amniotic fluid (AF) has thromboplastic activity. This activity was found to increase with the progression of pregnancy, showing a very high correlation coefficient (r = -0.86). In cases of pathologic pregnancies such as those associated with diabetes, toxemia, IUGR, and Rh incompatibility, the values of TAAF do not differ from normal pregnancies. However, in 7 of 10 cases of postmature pregnancies the TAAF was below 45 seconds while no preterm or term pregnancy showed TAAF of less than 45 seconds.
采用对奎克凝血酶原时间一步法的改良方法，测定了97例正常和病理妊娠孕妇羊水的促凝血活性（TAAF）。结果表明羊水具有促凝血活性。发现该活性随妊娠进展而增加，相关系数非常高（r = -0.86）。在糖尿病、毒血症、宫内生长受限和Rh血型不合等病理妊娠病例中，TAAF值与正常妊娠无差异。然而，在10例过期妊娠病例中有7例TAAF低于45秒，而早产或足月妊娠未出现TAAF低于45秒的情况。
