Finley W W
Pavlov J Biol Sci. 1977 Apr-Jun;12(2):93-111. doi: 10.1007/BF03004497.
Methodologic and clinical considerations are discussed in sensorimotor rhythm (SMR) biofeedback research on two dissimilar but severe epileptic males. The first case, an akinetic epileptic who prior to feedback training experienced 80-100 clinical seizures every 10 hours, showed considerable seizure reduction after 6 months of SMR and epileptiform training. A number of methodologic and instrumentation advances were pioneered with the akinetic patient: (1) development of and ultra-sharp band-pass filter; (2) use of epileptiform inhibit and feedback circuitry; (3) use of monetary rewards as additional incentive; (4) use of correlational analysis for evaluation of acquisition in the major dependent variables and; (5) use of noncontingent feedback and reinforcement as control techniques. The second case, a psychomotor epileptic, also showed therapeutic benefit from SMR training. Clinical information regarding the effect of anticonvulsant medications on the course and therapeutic outcome of SMR training are described. In conjunction with operant conditioning of 12 Hz activity, corresponding changes for other EEG parameters are examined.
本文讨论了针对两名不同类型但均患有严重癫痫的男性患者进行的感觉运动节律（SMR）生物反馈研究中的方法学和临床考量。第一个病例是一名运动不能性癫痫患者，在反馈训练前每10小时经历80 - 100次临床发作，在进行6个月的SMR和癫痫样放电训练后发作显著减少。针对该运动不能性患者开创了许多方法学和仪器方面的进展：（1）开发了超锐带通滤波器；（2）使用癫痫样放电抑制和反馈电路；（3）使用金钱奖励作为额外激励；（4）使用相关分析来评估主要因变量的习得情况；（5）使用非条件反馈和强化作为控制技术。第二个病例是一名精神运动性癫痫患者，也从SMR训练中显示出治疗益处。描述了关于抗惊厥药物对SMR训练过程和治疗结果影响的临床信息。结合12赫兹活动的操作性条件反射，研究了其他脑电图参数的相应变化。
