Finley W W, Smith H A, Etherton M D
Biol Psychol. 1975;2(3):189-203. doi: 10.1016/0301-0511(75)90019-8.
Sensorimotor rhythm (SMR) biofeedback training was attempted in a 13-year-old male with frequent epileptic seizures. Prior to training the subject was averaging almost eight clinical seizures an hour. The SMR filter was tuned sharply to 12 plus or minus 1 Hz. Feedback was conducted over approximately six months and continues to the present. In that time the subject's percentage of SMR increased from about 10%, prior to training, to 65% after the 34th training session. Correspondingly, his rate of clinical seizures decreased by a factor of 10 and a significant reduction in percentage of epileptiform discharges was noted. Beginning with trial 35, the subject was provided feedback of epileptiform activity in combination with 12 Hz activity. The combined effect of these two treatment variables was to reduce the trial-to-trial variance in the dependent variables of interest.
对一名患有频繁癫痫发作的13岁男性尝试进行感觉运动节律（SMR）生物反馈训练。在训练前，该受试者平均每小时有近8次临床发作。SMR滤波器被精确调谐到12加减1赫兹。反馈持续了大约六个月，一直持续到现在。在此期间，受试者的SMR百分比从训练前的约10%增加到第34次训练后的65%。相应地，他的临床发作率降低了10倍，并且癫痫样放电的百分比有显著降低。从第35次试验开始，向受试者提供癫痫样活动与12赫兹活动相结合的反馈。这两个治疗变量的综合作用是减少感兴趣的因变量的逐次试验方差。
