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Allele frequency distributions at seven DNA hypervariable loci in a population sample from Calabria (southern Italy).

作者信息

Rose G, De Luca M, Falcone E, Spadafora P, Carrieri G, De Benedictis G

机构信息

Cell Biology Department, University of Calabria, Italy.

出版信息

Gene Geogr. 1996 Aug;10(2):135-45.

PMID:9049623
Abstract

Genotype and allele frequencies at seven Variable Number of Tandem Repeats (VNTR) loci currently used for forensic purposes have been estimated in a population sample from Calabria (south Italy). DNA target regions relevant to four microsatellites (THO.1; REN.4; D12S67; DYS19) and three minisatellites (D1S80; 3'APOB; TPO.10) were amplified by Polymerase Chain Reaction (PCR) and analysed by electrophoresis and ethidium bromide or silver staining. For all loci, the observed genotypes were found to be in agreement with those expected by the Hardy-Weinberg equilibrium. Data on allele frequencies were in line with those found in sample groups from northern or central Italy, tested for some of the above polymorphisms.

摘要

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