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以HLA-DQα、YNZ22、3' APO B、HUMTH01和HUMVWA31A基因多态性为特征的克丘亚美洲印第安人群体。

Quechua Amerindian population characterized by HLA-DQ alpha, YNZ22, 3'APO B, HUMTH01, and HUMVWA31A polymorphisms.

作者信息

Gené M, Fuentes M, Huguet E, Piqué E, Bert F, Corella A, Pérez-Pérez A, Corbella J, Moreno P

机构信息

Department of Legal Medicine, Faculty of Medicine, University of Barcelona, Spain.

出版信息

J Forensic Sci. 1998 Mar;43(2):403-5.

PMID:9544552
Abstract

Allele and genotype frequencies of DNA polymorphisms were determined in a population sample of Quechua (n = 113) using the polymerase chain reaction (PCR). We report data on the frequencies of HLA-DQ alpha, YNZ22, 3'ApoB, HUMTH01 and HUMVWA31A alleles and the distribution of the different genotypes. No significant deviations between observed and expected numbers were found, thus assuming the Hardy-Weinberg equilibrium.

摘要

使用聚合酶链反应(PCR)测定了克丘亚人群样本(n = 113)中DNA多态性的等位基因和基因型频率。我们报告了HLA-DQα、YNZ22、3'ApoB、HUMTH01和HUMVWA31A等位基因频率的数据以及不同基因型的分布情况。未发现观察值与预期值之间存在显著偏差,因此假定处于哈迪-温伯格平衡。

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