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犬细小病毒感染、犬瘟热和犬传染性肝炎:瑞典犬类群体中的疫苗接种倾向和抗体反应

Canine parvovirus infection, canine distemper and infectious canine hepatitis: inclination to vaccinate and antibody response in the Swedish dog population.

作者信息

Olson P, Hedhammar A, Klingeborn B

机构信息

Department of Medicine and Surgery, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden.

出版信息

Acta Vet Scand. 1996;37(4):433-43. doi: 10.1186/BF03548083.

Abstract

The inclination of dog owners to vaccinate was investigated by sending a questionnaire to randomly selected Swedish dog-owning households. According to the owners (n = 538), 86.7% of the dogs had been vaccinated against CPV and 95.8% had been vaccinated against CD/ICH. The inclination to vaccinate mixed breeds was significantly lower than the inclination to vaccinate pure-bred dogs. In a second study titres of CPV, CD and CAV-1 virus antibodies were measured in 176 randomly selected dogs with known vaccination histories. CPV antibody titres > or = 1:80 were detected in 70.9% of the CPV vaccinated dogs. There was a significant difference in the fraction of dogs with CPV titre > or = 1:80 between the group last vaccinated with live attenuated vaccine and the group last vaccinated with inactivated vaccine. Titres of CD and CAV-1 virus antibodies > or = 1:16 were found in 86.1% and 91.6% of the vaccinated dogs respectively. The fraction of dogs with CAV-1 antibody titres > or = 1:16 was significantly greater in the group that received inactivated CAV-1 vaccine than in the group vaccinated with attenuated live CAV-2 vaccine. Approximately 50% of the dogs were booster vaccinated against all 3 diseases at one year of age.

摘要

通过向随机抽取的瑞典养狗家庭发送调查问卷,对狗主人的疫苗接种倾向进行了调查。根据狗主人(n = 538)的反馈,86.7%的狗接种了犬细小病毒(CPV)疫苗,95.8%的狗接种了犬瘟热/传染性肝炎(CD/ICH)疫苗。混种狗的疫苗接种倾向显著低于纯种狗。在第二项研究中,对176只已知疫苗接种史的随机抽取的狗测量了CPV、CD和犬腺病毒1型(CAV-1)病毒抗体滴度。在接种CPV疫苗的狗中,70.9%检测到CPV抗体滴度≥1:80。最后一次接种减毒活疫苗的组和最后一次接种灭活疫苗的组之间,CPV滴度≥1:80的狗的比例存在显著差异。接种疫苗的狗中,分别有86.1%和91.6%的狗检测到CD和CAV-1病毒抗体滴度≥1:16。接受灭活CAV-1疫苗的组中,CAV-1抗体滴度≥1:16的狗的比例显著高于接种减毒活CAV-2疫苗的组。约50%的狗在一岁时接受了针对所有三种疾病的加强疫苗接种。

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本文引用的文献

1
Canine parvovirus.犬细小病毒
Vet Clin North Am Small Anim Pract. 1993 May;23(3):555-68. doi: 10.1016/s0195-5616(93)50305-4.

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