Tokar' V I, Savchenko O N
Probl Endokrinol (Mosk). 1977 Jul-Aug;23(4):104-7.
The radioimmunological method was applied to the study of blood testosterone, LH, and FSH content in 41 men suffering from fluorosis, aged from 33 to 45 years. Nineteen men who had no contact with fluorine compounds served as control. In comparison with healthy individuals testosterone content proved to be decreased and FSH content elevated in patients with fluorosis. Blood LH content was increased only in those patients with fluorosis who had long contact with fluorine compounds (over 15 years). The changes in the blood hormone concentration were connected with disturbances of the hormonal, and, possibly, of the germenative function of the testes. The hypophysis proved to suffer less, and the changes of its function were apparently secondary in character.
采用放射免疫法对41例年龄在33至45岁的氟中毒男性患者的血液睾酮、促黄体生成素（LH）和促卵泡生成素（FSH）含量进行了研究。选取19名未接触氟化合物的男性作为对照。与健康个体相比，氟中毒患者的睾酮含量降低，FSH含量升高。仅在那些长期接触氟化合物（超过15年）的氟中毒患者中，血液LH含量增加。血液激素浓度的变化与睾丸的激素功能以及可能的生殖功能紊乱有关。垂体受影响较小，其功能变化显然是继发性的。
