Maincent G, Labadie H, Fabre M, Novello P, Derghal K, Patriarche C, Licht H
Hepatogastroenterology Department, Hopital Pierre Delafontaine, Saint Denis, France.
Dig Dis Sci. 1997 Feb;42(2):447-50. doi: 10.1023/a:1018855011180.
Although the incidence of syphilis is increasing, liver involvement in tertiary syphilis remains exceptional. We report a case of tertiary syphilis revealed by liver localization. The clinical picture was misleading, mimicking multinodular hepatic metastasis. The final diagnosis was suspected following a fine-needle ultrasound-guided biopsy of a liver nodule showing granulomas as well as acellular necrosis and confirmed by positive serum syphilitic reactions and the presence of spirochetes in the liver. The outcome was uneventful following antibiotic treatment. It is important to be aware of the misleading picture of the disease, which has a favorable prognosis provided that simple treatment is rapidly initiated.
尽管梅毒的发病率在上升，但三期梅毒累及肝脏的情况仍然罕见。我们报告一例以肝脏定位表现出来的三期梅毒病例。临床表现具有误导性，酷似多结节肝转移。最终诊断是在对肝脏结节进行超声引导下细针穿刺活检显示肉芽肿以及无细胞坏死之后怀疑的，并通过血清梅毒反应阳性和肝脏中存在螺旋体得以证实。抗生素治疗后病情平稳。认识到该疾病具有误导性的表现很重要，只要迅速开始简单治疗，其预后良好。
