孕早期的脐带囊肿

Umbilical cord cysts in early pregnancy.

作者信息

Ross J A, Jurkovic D, Zosmer N, Jauniaux E, Hacket E, Nicolaides K H

机构信息

Academic Department of Obstetrics and Gynecology, King's College School of Medicine and Dentistry, University of London, United Kingdom.

出版信息

Obstet Gynecol. 1997 Mar;89(3):442-5. doi: 10.1016/S0029-7844(96)00526-1.

DOI:10.1016/S0029-7844(96)00526-1

PMID:9052602

Abstract

OBJECTIVE

To assess the prevalence, morphologic characteristics, and natural history of umbilical cord cysts detected by ultrasound in the first trimester of pregnancy.

METHODS

This was an ultrasound screening study for the presence of umbilical cord cysts in 859 pregnant women with singleton live fetuses at 7-13 weeks' gestation. In all cases of cord cysts the scan was repeated fortnightly until the cyst resolved or a fetal abnormality was detected. All patients with ongoing pregnancies had detailed scans at 20 weeks. Infants and umbilical cords were examined after delivery for the presence of structural abnormalities.

RESULTS

Umbilical cord cysts were present in 29 (3.4%) of the 859 pregnancies. Fetal abnormalities were found in seven (26%) of the 27 cases with ongoing pregnancies. The fetus was more likely to be abnormal if the cyst was located near the placental or fetal extremity of the cord (relative risk [RR] 3.3; 95% confidence interval [CI] 1.3, 8.5) or paraxially (RR 3.8; 95% CI 1.2, 12.0) or if it persisted beyond 12 weeks' gestation (RR 7.7; 95% CI 3.2, 18.6).

CONCLUSIONS

The prevalence of umbilical cord cysts at 7-13 weeks' gestation is approximately 3%, and in more than 20% of cases there are fetal chromosomal or structural defects.

摘要

目的

评估孕早期超声检测出的脐带囊肿的患病率、形态特征及自然病史。

方法

这是一项针对859名单胎活胎孕妇在妊娠7至13周时进行脐带囊肿超声筛查的研究。对于所有脐带囊肿病例，每两周重复进行超声扫描，直至囊肿消失或检测到胎儿异常。所有继续妊娠的患者在孕20周时进行详细扫描。分娩后对婴儿和脐带进行检查，以确定是否存在结构异常。

结果

859例妊娠中有29例（3.4%）存在脐带囊肿。在27例继续妊娠的病例中，有7例（26%）发现胎儿异常。如果囊肿位于脐带胎盘端或胎儿端附近（相对危险度[RR] 3.3；95%置信区间[CI] 1.3，8.5）或近轴位（RR 3.8；95% CI 1.2，12.0），或者囊肿持续超过妊娠12周（RR 7.7；95% CI 3.2，18.6），则胎儿更有可能出现异常。