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蛋白激酶C缺陷型果蝇中无行为表现的学习

Learning without performance in PKC-deficient Drosophila.

作者信息

Kane N S, Robichon A, Dickinson J A, Greenspan R J

机构信息

Department of Biology and Center for Neural Science, New York University, New York, New York 10003, USA.

出版信息

Neuron. 1997 Feb;18(2):307-14. doi: 10.1016/s0896-6273(00)80270-6.

DOI:10.1016/s0896-6273(00)80270-6
PMID:9052800
Abstract

The performance of a task is often assumed to be a prerequisite for the learning of many tasks, including the associative conditioning of courtship in the fruit fly, Drosophila melanogaster. Transgenic flies specifically inhibited for the enzyme protein kinase C dissociate the acquisition of learning and memory from performance of the task. They fail to show immediate suppression of courtship but nonetheless develop normal memory of it.

摘要

执行一项任务通常被认为是学习许多任务的先决条件,包括果蝇(黑腹果蝇)求偶行为的联想性条件反射。对蛋白激酶C酶进行特异性抑制的转基因果蝇,将学习和记忆的获得与任务的执行分离开来。它们不会立即表现出求偶行为的抑制,但仍会形成对求偶行为的正常记忆。

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