Kharchenko M F, Rybakova L P, Golenko O D, Kornilova N V, Zakharov Iu M
Fiziol Zh Im I M Sechenova. 1996 May-Jun;82(5-6):18-25.
Literature review as well as own data on the role of glycosaminoglycans and proteoglycans of leukocytes, platelets and hemopoietic microenvironment are presented. These compounds are involved in the storage of lysosomal enzymes, cationic antibacterial polypeptides and other granular constituents of blood cells, take part in mediating of cellular interactions, occurring in hematopoiesis, phagocytosis, immunity and other processes. Due to the capacity to react with many substances, including enzymes, cell growth factors, cytokines, receptors, changing their conformation and biological activity glycosaminoglycans and proteoglycans can take part in regulation of cell adhesion, migration, proliferation differentiation and special functions of various types of hematopoietic and lymphoid cells.
本文综述了有关白细胞、血小板和造血微环境中糖胺聚糖和蛋白聚糖作用的文献以及自身数据。这些化合物参与溶酶体酶、阳离子抗菌多肽和血细胞其他颗粒成分的储存，参与介导造血、吞噬作用、免疫和其他过程中发生的细胞相互作用。由于糖胺聚糖和蛋白聚糖能够与许多物质（包括酶、细胞生长因子、细胞因子、受体）发生反应，改变它们的构象和生物活性，因此可以参与调节各种造血和淋巴细胞的细胞黏附、迁移、增殖分化及特殊功能。
