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招募老年人参与临床试验。

Recruiting older adults for clinical trials.

作者信息

Adams J, Silverman M, Musa D, Peele P

机构信息

Family Health Council, Inc., Pittsburgh, Pennsylvania 15222, USA.

出版信息

Control Clin Trials. 1997 Feb;18(1):14-26. doi: 10.1016/s0197-2456(96)00132-8.

Abstract

More than 400 community-dwelling older adults were recruited into a clinical trial which compared the effectiveness of diagnosis and treatment through geriatric assessment with that provided through usual community physician care. Six recruitment methods were utilized: referrals, solicitations, presentations, media, mailings, and fliers. Each method is described and its results reported in terms of numbers recruited, yield, and cost per participant. The most efficient method was referrals; the method producing the largest number was presentations; the least effective method was fliers. Problems and solutions are discussed, and guidelines for recruiting older adults are suggested. These guidelines include: monitoring with accompanying adaptation, targeting the groups most likely to benefit, providing incentives, and reducing uncertainty among potential participants.

摘要

400多名社区居住的老年人被招募进一项临床试验,该试验比较了通过老年医学评估进行诊断和治疗与通过社区普通医生护理进行诊断和治疗的效果。采用了六种招募方法:推荐、招揽、宣讲、媒体宣传、邮寄和传单。对每种方法都进行了描述,并报告了其招募人数、招募率和每位参与者成本的结果。最有效的方法是推荐;招募人数最多的方法是宣讲;最无效的方法是传单。讨论了问题及解决方案,并提出了招募老年人的指导方针。这些指导方针包括:进行监测并随时调整,针对最可能受益的群体,提供激励措施,以及减少潜在参与者的不确定性。

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