Gallén M, Pla J, Miguel A, Ibeas R, Carles J, Fabregat X
Servicio de Oncología, Hospital del Mar, Barcelona.
Rev Esp Enferm Dig. 1997 Jan;89(1):23-8.
A retrospective analysis of 20 patients with anal carcinoma treated at Hospital del Mar (Barcelona) from 1982 to 1995 was performed to evaluate clinical and pathological characteristics. This subset represents 2.1% of all the colon and rectum cancers registered in the same period. The mean age was 74 years (42-92), the female to male ratio was 1.5:1. The most frequent site was anal canal (80%) and the histological type was squamous cell and basaloid carcinomas in all cases. Five aged patients were not treated. Twelve patients were primary treated by abdominal perineal resection, 2 patients by radiotherapy and one by a local excision. The prognosis of 8 patients treated with palliative surgery was poor and none survived 30 months after surgery. In contrast, 4 of 5 patients are alive after radical surgery with a minimum 5 year follow-up. Two patients treated with radiotherapy are disease free at 7 and 13 months after treatment. The incidence of anal carcinoma is low, but our experience shows that it is diagnosed at an advanced stage and surgery is not always successful. Radiotherapy with or without chemotherapy, is an effective alternative.
对1982年至1995年在巴塞罗那海洋医院接受治疗的20例肛管癌患者进行回顾性分析，以评估其临床和病理特征。该亚组占同期登记的所有结肠直肠癌的2.1%。平均年龄为74岁（42 - 92岁），男女比例为1.5:1。最常见的部位是肛管（80%），所有病例的组织学类型均为鳞状细胞癌和基底样癌。5例老年患者未接受治疗。12例患者接受了腹会阴联合切除术，2例接受了放疗，1例接受了局部切除术。8例接受姑息性手术的患者预后较差，术后无1例存活30个月。相比之下，5例接受根治性手术的患者中有4例存活，随访至少5年。2例接受放疗的患者在治疗后7个月和13个月时无疾病。肛管癌的发病率较低，但我们的经验表明，其在晚期才被诊断出来，手术并不总是成功的。放疗联合或不联合化疗是一种有效的替代方法。
