Coøpkun Y, Bayraktaroğlu Z
Department of Paediatrics, Gaziantep University, Faculty of Medicine, Turkey.
Acta Paediatr. 1997 Feb;86(2):187-91. doi: 10.1111/j.1651-2227.1997.tb08866.x.
In 432 school children aged 7-15 years we investigated the following parameters; body mass index, blood pressure, total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol. Only 2.8% of children were considered to be obese. Of the children, 3.5% had systolic, 4.9% had diastolic and 3.9% had both blood pressures higher than the acceptable age- and sex-stratified values. The mean total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol levels were 3.37, 1.93 and 1.33 mmoll-1, respectively. In 31 (7.1%) of the children, total cholesterol levels were found to be above the risk cut-off level of 4.4 mmoll-1; in 39 (9%) of the children, low-density lipoprotein cholesterol levels were elevated above an acceptable upper limit of 2.84 mmoll-1. Significantly reduced high-density lipoprotein cholesterol values were observed in 8.8%. Mean total cholesterol and low-density lipoprotein cholesterol values were elevated significantly in hypertensive cases, while high-density lipoprotein cholesterol levels showed no difference. Sensitivity and the positive predictive value for selected total cholesterol cut-off points for determining elevated low-density lipoprotein cholesterol were 67% and 54%, respectively. These levels of risk are considerably lower than those found in studies in Western countries.
在432名7至15岁的学童中，我们调查了以下参数：体重指数、血压、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇。只有2.8%的儿童被认为肥胖。在这些儿童中，3.5%的儿童收缩压、4.9%的儿童舒张压以及3.9%的儿童收缩压和舒张压均高于按年龄和性别分层的可接受值。总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇的平均水平分别为3.37、1.93和1.33 mmol/L。在31名（7.1%）儿童中，发现总胆固醇水平高于4.4 mmol/L的风险临界值；在39名（9%）儿童中，低密度脂蛋白胆固醇水平升高至高于2.84 mmol/L的可接受上限。8.8%的儿童观察到高密度脂蛋白胆固醇值显著降低。高血压病例中总胆固醇和低密度脂蛋白胆固醇的平均水平显著升高，而高密度脂蛋白胆固醇水平无差异。用于确定低密度脂蛋白胆固醇升高的选定总胆固醇切点值对应的敏感度和阳性预测值分别为67%和54%。这些风险水平远低于西方国家研究中的发现。
