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Advances in the therapy for sepsis in children.

作者信息

Anderson M R, Blumer J L

机构信息

Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

出版信息

Pediatr Clin North Am. 1997 Feb;44(1):179-205. doi: 10.1016/s0031-3955(05)70469-7.

DOI:10.1016/s0031-3955(05)70469-7
PMID:9057790
Abstract

Sepsis remains a major clinical problem in children, with a high mortality rate. Recent discoveries have identified the major cytokines involved in sepsis and several anticytokine strategies have been used in clinical trials. Antiendotoxin, anticytokine, and even steroid therapy have been studied in humans, with limited success. Several of the clinical trials of immunotherapy in sepsis are reviewed, and the inherent pitfalls in the varied clinical approaches investigated are analyzed.

摘要

相似文献

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Advances in the therapy for sepsis in children.
Pediatr Clin North Am. 1997 Feb;44(1):179-205. doi: 10.1016/s0031-3955(05)70469-7.
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