健康儿童和青少年的全身骨矿物质含量。
Whole body bone mineral content in healthy children and adolescents.
作者信息
Mølgaard C, Thomsen B L, Prentice A, Cole T J, Michaelsen K F
机构信息
Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
出版信息
Arch Dis Child. 1997 Jan;76(1):9-15. doi: 10.1136/adc.76.1.9.
Abstract
Data from healthy children are needed to evaluate bone mineralisation during childhood. Whole body bone mineral content (BMC) and bone area were examined by dual energy x ray absorptiometry (Hologic 1000/W) in healthy girls (n = 201) and boys (n = 142) aged 5-19 years. Centile curves for bone area for age, BMC for age, bone area for height, and BMC for bone area were constructed using the LMS method. Bone mineral density calculated as BMC/bone area is not useful in children as it is significantly influenced by bone size. Instead, it is proposed that bone mineralisation is assessed in three steps: height for age, bone area for height, and BMC for bone area. These three steps correspond to three different causes of reduced bone mass: short bones, narrow bones, and light bones.
摘要
需要来自健康儿童的数据来评估儿童期的骨矿化情况。采用双能X线吸收法（Hologic 1000/W）对201名健康女孩和142名健康男孩（年龄5 - 19岁）进行全身骨矿物质含量（BMC）和骨面积检测。使用LMS方法构建年龄别骨面积、年龄别BMC、身高别骨面积以及骨面积别BMC的百分位数曲线。以BMC/骨面积计算的骨密度对儿童无用，因为它受骨骼大小的显著影响。相反，建议通过三个步骤评估骨矿化：年龄别身高、身高别骨面积以及骨面积别BMC。这三个步骤分别对应骨量减少的三种不同原因：骨骼短小、骨骼狭窄和骨骼较轻。
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