Russell I F, Wang M
Department of Anaesthesia, Hull Royal Infirmary, Kingston upon Hull, East Riding of Yorkshire.
Br J Anaesth. 1997 Jan;78(1):3-9. doi: 10.1093/bja/78.1.3.
Using the isolated forearm technique (IFT), we wished to determine if patients known to be unresponsive to commands during general anaesthesia with nitrous oxide, halothane and neuromuscular blocking agents had any evidence of explicit or implicit recall. Two groups of women, studied in a single-blind sequential block design, heard different tapes, either a command and information tape (n = 34) or radio static (n = 34), throughout surgery. Four women (two radio static, two command) had unequivocal evidence of explicit recall for a period near the beginning or end of the procedure, at a time when the IFT was not being used. With or without hypnosis, category generation, serial position of category exemplars and word association tests did not reveal evidence of priming. We conclude that during light general anaesthesia with nitrous oxide, halothane and atracurium, patients had neither explicit nor implicit memory for information presented during a period when they are known to be unresponsive to commands.
采用孤立前臂技术(IFT),我们希望确定那些已知在使用氧化亚氮、氟烷和神经肌肉阻滞剂进行全身麻醉期间对指令无反应的患者是否有任何明确或隐性记忆的证据。两组女性采用单盲序贯分组设计进行研究,在整个手术过程中,她们听不同的磁带,一组听指令和信息磁带(n = 34),另一组听无线电噪声(n = 34)。四名女性(两名听无线电噪声,两名听指令)在手术开始或结束附近的一段时间内有明确的明确记忆证据,而此时未使用IFT。无论有无催眠、类别生成、类别范例的系列位置和词语联想测试,均未发现启动效应的证据。我们得出结论,在使用氧化亚氮、氟烷和阿曲库铵进行浅全身麻醉期间,患者对已知对指令无反应的时间段内呈现的信息既没有明确记忆也没有隐性记忆。