Bury T, Paulus P, Dowlati A, Corhay J L, Rigo P, Radermecker M F
Pneumology Department, CHU Sart Tilman, Liège, Belgium.
Thorax. 1997 Feb;52(2):187-9. doi: 10.1136/thx.52.2.187.
Positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) is an accurate method for differentiating benign from malignant disease. The use of FDG-PET for the aetiological diagnosis of pleural disease was investigated in 25 patients.
PET was performed on each subject before invasive procedures were used to determine the aetiological diagnosis. The PET data were analysed by visual interpretation of coronal, sagittal, and transverse slices.
Sixteen patients were found to have malignant pleural disease and nine had benign disease. All patients with histologically confirmed malignant disease showed FDG uptake within the pleural thickening which was intense in 14 cases and moderate in two. PET imaging showed the absence of FDG uptake and correctly categorised seven non-malignant lesions. Two patients with infectious pleural diseases showed a localised and moderate FDG uptake.
Our preliminary results suggest that FDG-PET could be an effective tool for differentiating between benign and malignant pleural diseases.
18氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）是鉴别良性与恶性疾病的一种准确方法。我们对25例患者使用FDG-PET进行胸膜疾病的病因诊断研究。
在采用侵入性检查确定病因诊断之前，对每个受试者进行PET检查。通过对冠状面、矢状面和横断面切片的视觉解读来分析PET数据。
发现16例患者患有恶性胸膜疾病，9例患有良性疾病。所有经组织学证实为恶性疾病的患者，其胸膜增厚部位均显示FDG摄取，其中14例摄取强烈，2例摄取中等。PET成像显示无FDG摄取，并正确分类了7例非恶性病变。2例感染性胸膜疾病患者显示局部中等程度的FDG摄取。
我们的初步结果表明，FDG-PET可能是鉴别良性与恶性胸膜疾病的有效工具。
