Kuboyama T, Hori A, Sato T, Mikami T, Yamaki T, Ueda S
Department of Neurosurgery, Ohmihachiman City Hospital, Shiga, Japan.
Electroencephalogr Clin Neurophysiol. 1997 Feb;102(2):125-31. doi: 10.1016/s0921-884x(96)95054-7.
Using transcranial Doppler ultrasonography, we measured in 6 healthy young men cerebral blood flow velocity (CBFV) in the middle cerebral artery as well as oxygen saturation by a non-invasive method. Continuous recordings were taken starting from a point before the onset of sleep, throughout the duration of normal nighttime sleep, ending after awakening. During stages 2, 3 and 4, CBFV was approximately 15% lower than during the waking period preceding sleep. CBFV during rapid eye movement sleep did not differ from the presleep waking value, whereas the postsleep waking value was 6.6% lower. In 5 subjects CBFV showed a transient rise after sleep onset. Oxygen saturation was lower during sleep than during waking.
我们使用经颅多普勒超声检查，通过无创方法测量了6名健康年轻男性大脑中动脉的脑血流速度（CBFV）以及血氧饱和度。从睡眠开始前的一个时间点开始进行连续记录，贯穿正常夜间睡眠的整个时段，直至醒来后结束。在睡眠2期、3期和4期，CBFV比睡眠前的清醒期约低15%。快速眼动睡眠期的CBFV与睡眠前清醒时的值没有差异，而睡眠后清醒时的值低6.6%。在5名受试者中，CBFV在睡眠开始后出现短暂升高。睡眠期间的血氧饱和度低于清醒时。
