Manni E, Petrosini L
Institute of Human Physiology, Catholic University, Rome, Italy.
Trends Neurosci. 1997 Mar;20(3):112-6. doi: 10.1016/s0166-2236(96)10077-1.
In 1891, Luigi Luciani published his famous monograph on the cerebellum and formulated his triad of the cerebellar symptoms: atonia, asthenia and astasia, which explained all troubles provoked by cerebellar lesions; later he added a fourth sign, dysmetria. In spite of the fact that it was advanced in a pre-electrophysiological period, Luciani's interpretation of the cerebellar role in many motor functions survives more than a century later and his terminology has entered the routine of the neurological examination. With the modern knowledge of cerebellar circuitries, we can state that Luciani rightly pointed out the role of the cerebellum in regulating postural tone and muscular force, and that conversely he was wrong in denying cerebellar influence in co-ordination of multi-joint movements and the somatotopic localizations in the cerebellar cortex and nuclei. In spite of this, Luciani's work represents a milestone in cerebellar physiology.
1891年,路易吉·卢恰尼发表了他关于小脑的著名专著,并阐述了他的小脑症状三联征:张力缺失、肌无力和站立不稳,这解释了由小脑病变引发的所有问题;后来他又补充了第四个体征,即辨距障碍。尽管这一理论是在电生理学时代之前提出的,但卢恰尼对小脑在许多运动功能中所起作用的解释在一个多世纪后依然存在,他的术语也已成为神经学检查的常用词汇。基于对小脑回路的现代认识,我们可以说,卢恰尼正确地指出了小脑在调节姿势张力和肌肉力量方面的作用,相反,他否认小脑对多关节运动协调以及小脑皮质和核团中躯体定位的影响则是错误的。尽管如此,卢恰尼的工作仍是小脑生理学领域的一个里程碑。