羊瘙痒症仅仅是一种遗传性疾病吗？ - Suppr

Suppr

超能文献

Is scrapie solely a genetic disease?

作者信息

Hunter N, Cairns D, Foster J D, Smith G, Goldmann W, Donnelly K

出版信息

Nature. 1997 Mar 13;386(6621):137. doi: 10.1038/386137a0.

DOI:10.1038/386137a0

PMID:9062185

Abstract

摘要

相似文献

Is scrapie solely a genetic disease?羊瘙痒症仅仅是一种遗传性疾病吗？

Nature. 1997 Mar 13;386(6621):137. doi: 10.1038/386137a0.

Scrapie-free Merino and Poll Dorset sheep from Australia and New Zealand have normal frequencies of scrapie-susceptible PrP genotypes.

J Gen Virol. 1998 Aug;79 ( Pt 8):2079-82. doi: 10.1099/0022-1317-79-8-2079.

Scrapie resistance alleles are not associated with lower prolificity in Rasa Aragonesa sheep.抗瘙痒病等位基因与阿拉贡纳绵羊较低的繁殖力无关。

Res Vet Sci. 2006 Aug;81(1):37-9. doi: 10.1016/j.rvsc.2005.10.001. Epub 2005 Nov 28.

Lateral transmission of natural scrapie to scrapie-free New Zealand sheep placed in an endemically infected UK flock.将无痒病的新西兰绵羊置于英国地方性感染羊群中时，自然痒病的横向传播情况。

Vet Rec. 2006 Nov 4;159(19):633-4. doi: 10.1136/vr.159.19.633.

Frequency of PRNP genotypes in common New Zealand sheep breeds.

Vet Rec. 2008 Oct 11;163(15):453-4. doi: 10.1136/vr.163.15.453.

Prion protein allele A136 H154Q171 is associated with high susceptibility to scrapie in purebred and crossbred German Merinoland sheep.朊病毒蛋白等位基因A136 H154Q171与纯种和杂交德国美利奴羊对羊瘙痒病的高易感性相关。

Arch Virol. 2004 Aug;149(8):1571-80. doi: 10.1007/s00705-004-0303-1. Epub 2004 Apr 5.

Diagnosis and PrP genotype target of scrapie in clinically healthy sheep of Massese breed in the framework of a scrapie eradication programme.在羊瘙痒病根除计划框架下，对马塞塞品种临床健康绵羊的羊瘙痒病诊断及PrP基因型目标

Arch Virol. 2005 Oct;150(10):1959-76. doi: 10.1007/s00705-005-0564-3. Epub 2005 Jun 3.

Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene.

J Gen Virol. 1991 Oct;72 ( Pt 10):2411-7. doi: 10.1099/0022-1317-72-10-2411.

Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan.

J Gen Virol. 1995 Oct;76 ( Pt 10):2577-81. doi: 10.1099/0022-1317-76-10-2577.

Swaledale sheep affected by natural scrapie differ significantly in PrP genotype frequencies from healthy sheep and those selected for reduced incidence of scrapie.受自然痒病影响的斯瓦尔代尔羊在朊蛋白基因型频率上与健康羊以及那些因痒病发病率降低而被选育的羊存在显著差异。

J Gen Virol. 1993 Jun;74 ( Pt 6):1025-31. doi: 10.1099/0022-1317-74-6-1025.

引用本文的文献

Genetic Polymorphism at 15 Codons of the Prion Protein Gene in 156 Goats from Romania.罗马尼亚 156 只山羊朊病毒蛋白基因 15 个密码子的遗传多态性。

Genes (Basel). 2022 Jul 23;13(8):1316. doi: 10.3390/genes13081316.

Genetic profile of scrapie codons 146, 211 and 222 in the PRNP gene locus in three breeds of dairy goats.PRNP 基因座中 146、211 和 222 密码子的羊瘙痒病遗传特征在三个奶山羊品种中的研究。

PLoS One. 2018 Jun 7;13(6):e0198819. doi: 10.1371/journal.pone.0198819. eCollection 2018.

Predicting the impact of selection for scrapie resistance on PRNP genotype frequencies in goats.预测选择抗瘙痒病对山羊 PRNP 基因型频率的影响。

Vet Res. 2018 Mar 6;49(1):26. doi: 10.1186/s13567-018-0518-x.

Behind the potential evolution towards prion resistant species.在向抗朊病毒物种潜在进化的背后。

Prion. 2018 Mar 4;12(2):83-87. doi: 10.1080/19336896.2018.1435935. Epub 2018 Feb 20.

An Amino Acid Substitution Found in Animals with Low Susceptibility to Prion Diseases Confers a Protective Dominant-Negative Effect in Prion-Infected Transgenic Mice.在对朊病毒疾病易感性低的动物中发现的一种氨基酸取代赋予了朊病毒感染的转基因小鼠保护性显性负效应。

Mol Neurobiol. 2018 Jul;55(7):6182-6192. doi: 10.1007/s12035-017-0832-8. Epub 2017 Dec 20.

Evidence in sheep for pre-natal transmission of scrapie to lambs from infected mothers.绵羊感染朊病毒病的产前传播证据：来自感染母体的羔羊。

PLoS One. 2013 Nov 18;8(11):e79433. doi: 10.1371/journal.pone.0079433. eCollection 2013.

Genotyping and surveillance for scrapie in Finnish sheep.芬兰绵羊的朊病毒基因分型和监测。

BMC Vet Res. 2012 Jul 25;8:122. doi: 10.1186/1746-6148-8-122.

Resistance to classical scrapie in experimentally challenged goats carrying mutation K222 of the prion protein gene.携带朊病毒蛋白基因 K222 突变的实验性攻毒山羊对经典瘙痒病的抗性。

Vet Res. 2012 Feb 1;43(1):8. doi: 10.1186/1297-9716-43-8.

Microsecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie.绵羊朊病毒蛋白的微秒展开动力学揭示了与经典瘙痒病易感性相关的中间态。

Biophys J. 2011 Sep 7;101(5):1221-30. doi: 10.1016/j.bpj.2011.07.024.

Allelic frequency and genotypes of prion protein at codon 136 and 171 in Iranian Ghezel sheep breeds.伊朗 Ghezel 绵羊品种 136 和 171 密码子的朊病毒蛋白等位基因频率和基因型。

Prion. 2011 Jul-Sep;5(3):228-31. doi: 10.4161/pri.5.3.16098. Epub 2011 Jul 1.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验