Hashimoto M, Mikami T, Kudo T, Sugawara T, Yasuda H
Department of Cardiovascular Medicine, Hokkaido University School of Medicine, Sapporo.
J Cardiol. 1990;20(4):871-8.
To assess the mode of left ventricular hypertrophy in hypertrophic cardiomyopathy (HCM), two-dimensional echocardiography was performed in 15 patients with asymmetric septal hypertrophy and in 13 normal subjects. The long-axis diameter (LxD) was defined as the distance from the midpoint between the anterior annulus of the aortic valve and the posterior annulus of the mitral valve to the apex in the apical long-axis image. In the parasternal long-axis image, the long axis of the left ventricle (LV) was determined by overlaying the parasternal image on the apical image. The external diameter (ExD) and the internal diameter (InD) of the LV at chordal level were measured in the direction of the short axis. The anterior part (-a) and the posterior part (-p) of both ExD and InD, which were divided by the long axis, were also measured. LxD, ExD, ExD-a, ExD-p and InD-p in HCM were greater than those in the normal subjects. Thus, the interventricular septum (IVS) in HCM was thickened inwardly and outwardly. In contrast, the left ventricular posterior wall (PW) in HCM showed only outward deviation. Thickness of the IVS and PW, and the excursion of the PW in HCM were greater than those in the normals, but the excursion of the IVS in HCM was smaller than those in the normals. We concluded that outward expansion of the IVS and PW occurs in HCM and distinct narrowing of the LV occurs only on the septal side in HCM.(ABSTRACT TRUNCATED AT 250 WORDS)
为评估肥厚型心肌病(HCM)中左心室肥厚的模式,对15例不对称性室间隔肥厚患者和13名正常受试者进行了二维超声心动图检查。长轴直径(LxD)定义为在心尖长轴图像中从主动脉瓣前瓣环与二尖瓣后瓣环之间的中点到心尖的距离。在胸骨旁长轴图像中,通过将胸骨旁图像叠加在心尖图像上来确定左心室(LV)的长轴。在短轴方向上测量LV在腱索水平的外径(ExD)和内径(InD)。还测量了ExD和InD被长轴分割后的前部(-a)和后部(-p)。HCM患者的LxD、ExD、ExD-a、ExD-p和InD-p均大于正常受试者。因此,HCM患者的室间隔(IVS)向内外增厚。相比之下,HCM患者的左心室后壁(PW)仅向外偏移。HCM患者的IVS和PW厚度以及PW的偏移大于正常人,但HCM患者的IVS偏移小于正常人。我们得出结论,HCM患者的IVS和PW向外扩张,且HCM患者的LV仅在室间隔侧出现明显狭窄。(摘要截取自250字)