Mendes de Leon C F, Beckett L A, Fillenbaum G G, Brock D B, Branch L G, Evans D A, Berkman L F
Department of Epidemiology and Public Health, Yale University, New Haven, CT, USA.
Am J Epidemiol. 1997 Mar 15;145(6):488-97. doi: 10.1093/oxfordjournals.aje.a009136.
This study compared the odds of becoming disabled and recovering from disability among blacks and whites aged 65 years and over in two sites of the Established Populations for Epidemiologic Studies of the Elderly (EPESE) project. The authors examined the influence of mortality differences, socioeconomic status, and health-related factors on racial differences in risk of disability and recovery. A Markov model was employed using nine waves of data from the New Haven, Connecticut, site (529 blacks, 2,219 whites) and seven waves of the North Carolina (Piedmont) site (2,260 blacks, 1,876 whites), collected between 1982 and 1992. Blacks below age 75 years had an increased risk of developing disability relative to whites in New Haven (odds ratio (OR) at age 65 years = 3.33, 95% confidence interval (CI) 2.13-5.22) as well as in North Carolina (OR at age 65 years = 1.58, 95% CI 1.25-1.99). This excess risk diminished with increasing age, and crossed over in New Haven (OR at age 85 years = 0.45, 95% CI 0.22-0.95), but not in North Carolina (OR at age 85 years = 1.22, 95% CI 0.98-1.51). Adjustment for socioeconomic and health-related factors only partially reduced the excess disability risk among blacks below age 75 years in New Haven, but eliminated the difference in disability risk between blacks and whites in North Carolina. Blacks below age 75 years also had higher mortality risks at both sites. There were no consistent racial differences in recovery from disability.
本研究比较了老年流行病学研究既定人群(EPESE)项目两个地点65岁及以上黑人和白人出现残疾及从残疾中恢复的几率。作者研究了死亡率差异、社会经济地位和健康相关因素对残疾风险和恢复方面种族差异的影响。使用了来自康涅狄格州纽黑文地点的九波数据(529名黑人,2219名白人)和北卡罗来纳州(皮埃蒙特)地点的七波数据(2260名黑人,1876名白人)构建马尔可夫模型,这些数据收集于1982年至1992年之间。在纽黑文,75岁以下的黑人相对于白人有更高的残疾发生风险(65岁时的优势比(OR)= 3.33,95%置信区间(CI)2.13 - 5.22),在北卡罗来纳州也是如此(65岁时的OR = 1.58,95% CI 1.25 - 1.99)。这种额外风险随着年龄增长而降低,在纽黑文出现了交叉(85岁时的OR = 0.45,95% CI 0.22 - 0.95),但在北卡罗来纳州没有(85岁时的OR = 1.22,95% CI 0.98 - 1.51)。对社会经济和健康相关因素进行调整后,仅部分降低了纽黑文75岁以下黑人的额外残疾风险,但消除了北卡罗来纳州黑人和白人在残疾风险上的差异。两个地点75岁以下的黑人也有更高的死亡风险。在从残疾中恢复方面没有一致的种族差异。