Sone Y, Isoda-Johmura M, Misaki A
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University, Japan.
Biosci Biotechnol Biochem. 1996 Feb;60(2):213-5. doi: 10.1271/bbb.60.213.
A heteropolysaccharide and a beta-D-glucan were isolated from a lichen, Gyrophora esculenta Miyoshi (Iwatake), by cold water and alkali extractions, respectively. The chemical properties of purified polysaccharides were examined by acid hydrolysis, methylation, and GC-MS. The heteropolysaccharide is a highly branched galactomannan-type polysaccharide, containing an alpha-(1->6)-linked D-mannan backbone, and the glucan is a linear (1->6)-beta-D-glucan. With regard to the antitumor activity, both the galactomannan and (1->6)-beta-D-glucan had moderate inhibition activities on Sarcoma 180, but lower than those of branched (1->3)-beta-D-glucans.
分别通过冷水和碱提取法，从地衣石耳（Gyrophora esculenta Miyoshi，岩茸）中分离出一种杂多糖和一种β-D-葡聚糖。通过酸水解、甲基化和气相色谱-质谱联用仪对纯化多糖的化学性质进行了研究。该杂多糖是一种高度分支的半乳甘露聚糖型多糖，含有α-(1→6)-连接的D-甘露聚糖主链，而葡聚糖是一种线性(1→6)-β-D-葡聚糖。关于抗肿瘤活性，半乳甘露聚糖和(1→6)-β-D-葡聚糖对肉瘤180均有中等程度的抑制活性，但低于分支的(1→3)-β-D-葡聚糖。
