Inhibitory effects of caffeic acid ethyl ester on H2O2-induced cytotoxicity and DNA single-strand breaks in Chinese hamster V79 cells.
作者信息
Nakayama T, Yamada M, Osawa T, Kawakishi S
机构信息
School of Food and Nutritional Sciences, University of Shizuoka, Japan.
出版信息
Biosci Biotechnol Biochem. 1996 Feb;60(2):316-8. doi: 10.1271/bbb.60.316.
PMID:9063980
Abstract
Cytotoxicity and DNA single-strand breaks caused by H2O2 were assessed by a colony formation assay and a DNA precipitation assay, respectively, with Chinese hamster V79 cells. In both assays, caffeic acid ethyl ester showed protective effects. The structure-activity relationship showed that the o-dihydroxy structure of caffeic acid ethyl ester was essential for the protective effects.
摘要
Zotero 插件