Wanke T
Ludwig Boltzmann-Institut für Umweltpneumologie, Krankenhauses der Stadt Wien-Lainz.
Wien Med Wochenschr. 1996;146(23):585-7.
The increased airway resistance and hyperinflation characteristic of chronic obstructive pulmonary disease (COPD) affect respiratory muscle function, particularly that of the diaphragm. The compensatory changes of the breathing pattern due to expiratory flow limitation lead to a further increase of the mechanical load on the ventilatory muscles during forced ventilation. Therapeutic strategies which reduce hyperinflation and the increased airway obstruction, improve the neuromechanical efficiency of the inspiratory muscles.
慢性阻塞性肺疾病（COPD）的气道阻力增加和肺过度充气特征会影响呼吸肌功能，尤其是膈肌的功能。由于呼气气流受限导致的呼吸模式代偿性改变，会使强制通气期间通气肌的机械负荷进一步增加。降低肺过度充气和气道阻塞加重情况的治疗策略，可提高吸气肌的神经机械效率。
