Buma P, Lamerigts N, Schreurs B W, Gardeniers J, Versleyen D, Slooff T J
Institute of Orthopedics, University Hospital Nijmegen, The Netherlands.
Acta Orthop Scand. 1996 Dec;67(6):536-40. doi: 10.3109/17453679608997751.
We took core biopsies from the acetabulum in 8 patients (at reoperation) after a previous revision with impacted cancellous allograft chips in combination with cement. Except for one biopsy specimen, the graft showed different stages of incorporation. In the specimens taken at 4 months, revascularization of the graft was found. Osteoclasts had removed parts of the graft, while woven bone had formed on the remnants of the graft and in the stroma that was invading the graft. Subsequent specimens showed that this mixture of graft and new bone was in due time remodeled into a normal trabecular bony structure with viable bone marrow that contained little or no remnants of the original graft. The graft-cement interface was present in 4 biopsies taken at 1, 22, 28, and 72 months. The specimen obtained 28 months after revision showed vital bone locally in direct contact with the cement layer; however, a soft tissue interface predominated.
我们对8例患者（再次手术时）的髋臼进行了核心活检，这些患者此前接受过异体松质骨嵌体联合骨水泥的翻修手术。除一份活检标本外，移植物显示出不同程度的整合阶段。在术后4个月采集的标本中，发现移植物有血管再生。破骨细胞已去除部分移植物，而编织骨则在移植物残余部分以及侵入移植物的基质中形成。随后的标本显示，这种移植物与新骨的混合物适时地重塑为具有存活骨髓的正常小梁骨结构，其中几乎没有或没有原始移植物的残余物。在术后1个月、22个月、28个月和72个月采集的4份活检标本中存在移植物 - 骨水泥界面。翻修术后28个月获得的标本显示，局部有活性骨与水泥层直接接触；然而，软组织界面占主导。
