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Striatal dopamine D1 receptors in narcolepsy: a PET study with [11C]NNC 756.

作者信息

Rinne J O, Hublin C, Partinen M, Ruottinen H, Någren K, Lehikoinen P, Ruotsalainen U, Laihinen A

机构信息

Department of Neurology, University of Turku, Finland.

出版信息

J Sleep Res. 1996 Dec;5(4):262-4. doi: 10.1111/j.1365-2869.1996.00262.x.

Abstract

We investigated dopamine D1 receptors in the putamen and caudate nucleus with positron emission tomography in six patients with narcolepsy and five healthy controls using [11C]NNC 756 as ligand. The caudate-to-cerebellum and putamen-to-cerebellum ratios of [11C]NNC 756 were within normal limits in patients with narcolepsy. No evidence of increased D1 receptor binding in narcolepsy was found.

摘要

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