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[原发性高脂蛋白血症的诊断]

[Diagnosis of primary hyperlipoproteinemias].

作者信息

Singer P

出版信息

Z Gesamte Inn Med. 1977 May 1;32(9):129-33 concl.

PMID:906591
Abstract

The diagnostics of hyperlipoproteinaemias is essentially based on the proof of biochemical parameters. The simultaneous determination of triglycerides and cholesterol in the serum is the most important measure for establishing disturbances of the lipid metabolism. The behaviour of these two lipids, the consideration of the serum and the lipoprotein electrophoresis in most cases make possible a classification according to the distributed all over the world and clinically relevant division according to Fredrickson. Loading tests for the early recognition of hyperlipoproteinaemias - analogus to protodiabetes - are hitherto not yet known. Within the diagnostics shoude be taken into consideration that hyperliproproteinaemias are frequently associated with other metabolic diseases (obesity, gout, diabetes mellitus, hypertension) as so-called metabolic syndrome.

摘要

高脂蛋白血症的诊断主要基于生化参数的验证。血清中甘油三酯和胆固醇的同时测定是确定脂质代谢紊乱的最重要措施。这两种脂质的表现、血清的考量以及脂蛋白电泳在大多数情况下使得根据世界各地分布的情况并按照弗雷德里克森进行临床相关分类成为可能。迄今为止,类似于早期糖尿病的用于早期识别高脂蛋白血症的负荷试验尚不为人所知。在诊断过程中应考虑到,高脂蛋白血症常与其他代谢性疾病(肥胖、痛风、糖尿病、高血压)相关,即所谓的代谢综合征。

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