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醋酸可的松对微小膜壳绦虫(绦虫纲:圆叶目)代谢的影响

The effect of cortisone acetate on the metabolism of Hymenolepis microstoma (cestoda:cyclophyllidea).

作者信息

Khan Z I, De Rycke P H

出版信息

Z Parasitenkd. 1977 Jul 29;52(3):267-74. doi: 10.1007/BF00380546.

DOI:10.1007/BF00380546
PMID:906632
Abstract

Hymenolepis microstoma grown in mice, treated with 1.25 mg cortisone acetate every second day, are heavier and have a significantly higher glycogen content than those in control mice. The dry/wet weight ratio and protein content however are unaffected. It is suggested that the increase in glycogen reserve and weight in H. microstoma from cortisone-treated mice is due to an immunosuppressive effect and better nutritional environment rather than hormonal action. Inclusion of 0.1 mg of cortisone per 100 ml of culture medium produces no change in worm weight in vitro. Single worm infections result in 100% recovery, but 30 worm infections provoke a rejection process which can be suppressed partially by administration of cortisone acetate.

摘要

每隔一天用1.25毫克醋酸可的松处理的、在小鼠体内生长的微小膜壳绦虫,比对照小鼠体内的绦虫更重,糖原含量也显著更高。然而,干/湿重比和蛋白质含量不受影响。有人认为,用可的松处理的小鼠体内微小膜壳绦虫的糖原储备和体重增加是由于免疫抑制作用和更好的营养环境,而非激素作用。每100毫升培养基中加入0.1毫克可的松,在体外对虫体重量没有影响。单条虫感染可导致100%的回收率,但30条虫感染会引发排斥反应,醋酸可的松给药可部分抑制这种反应。

相似文献

1
The effect of cortisone acetate on the metabolism of Hymenolepis microstoma (cestoda:cyclophyllidea).醋酸可的松对微小膜壳绦虫(绦虫纲:圆叶目)代谢的影响
Z Parasitenkd. 1977 Jul 29;52(3):267-74. doi: 10.1007/BF00380546.
2
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本文引用的文献

1
The influence of population density on patterns and physiology of growth in Hymenolepis diminuta (Cestoda:Cyclophyllidea) in the definitive host.种群密度对微小膜壳绦虫(绦虫纲:圆叶目)在终末宿主体内生长模式和生理的影响。
Exp Parasitol. 1961 Nov;11:332-71. doi: 10.1016/0014-4894(61)90040-6.
2
The natural resistance of the white rat to Nematospiroides dubius and the effect of cortisone on this resistance.白鼠对 dubius 类圆线虫的天然抵抗力以及可的松对这种抵抗力的影响。 (注:原文中 Nematospiroides dubius 可能存在拼写错误,准确的线虫名称是 Heligmosomoides polygyrus bakeri,中文名多为贝氏类圆线虫,但需根据原文上下文判断是否有误,此处暂按原文翻译)
J Parasitol. 1960 Apr;46:175-85.
3
Metabolism of hydrocortisone during inflammation.
炎症期间氢化可的松的代谢
Endocrinology. 1958 Apr;62(4):455-62. doi: 10.1210/endo-62-4-455.
4
On the localization of steroid hormones in connective tissue.关于类固醇激素在结缔组织中的定位
Ann N Y Acad Sci. 1956 Nov 16;64(4):466-75. doi: 10.1111/j.1749-6632.1956.tb36819.x.
5
Some effects of cortisone in mice with acquired immunity to Trichinella spiralis.可的松对获得旋毛虫免疫力小鼠的某些作用。
J Infect Dis. 1956 Jan-Feb;98(1):39-44. doi: 10.1093/infdis/98.1.39.
6
A colorimetric micro-method for the determination of glycogen in tissues.一种用于测定组织中糖原的比色微量法。
Biochem J. 1954 Apr;56(4):646-8. doi: 10.1042/bj0560646.
7
Comparison of the effect of 11-ketoprogesterone, 11alpha-hydroxyprogesterone and 11 beta-hydroxyprogesterone upon the glycosuria of the partially depancreatized rat.11-酮孕酮、11α-羟基孕酮和11β-羟基孕酮对部分胰腺切除大鼠糖尿作用的比较。
Endocrinology. 1953 Aug;53(2):221-5. doi: 10.1210/endo-53-2-221.
8
Use of cortisone derivatives to inhibit resistance to Nippostrongylus brasiliensis and to study the fate of parasites in resistant hosts.使用可的松衍生物抑制对巴西日圆线虫的抗性并研究抗性宿主体内寄生虫的命运。
Parasitology. 1965 Nov;55(4):723-30.
9
Studies on the immunity of albino mice to Trichuris muris. Suppression of immunity by cortisone acetate.白化小鼠对鼠鞭虫免疫的研究。醋酸可的松对免疫的抑制作用。
Parasitology. 1970 Apr;60(2):229-37. doi: 10.1017/s0031182000078070.
10
The effect of immunosuppressants on the development of Hymenolepis diminuta in mice.免疫抑制剂对小鼠微小膜壳绦虫发育的影响。
Parasitology. 1972 Aug;65(1):111-20. doi: 10.1017/s0031182000044279.