Nemoto A, Tanaka Y, Karasaki Y, Komaki H, Yazawa K, Mikami Y, Tojo T, Kadowaki K, Tsuda M, Kobayashi J
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
J Antibiot (Tokyo). 1997 Jan;50(1):18-21. doi: 10.7164/antibiotics.50.18.
New benz[alpha]anthraquinone antibiotics (brasiliquinones A, B and C) with an ethyl group at C-3 were isolated. The producer was identified as Nocardia brasiliensis. The antibiotics were active against Gram-positive bacteria including Mycobacterium sp., but not active against Gram-negative bacteria or fungi. They were also active against multiple drug-resistant P388/ADR tumor cells.
分离出了在C-3位带有一个乙基的新型苯并[α]蒽醌类抗生素（巴西醌A、B和C）。其产生菌被鉴定为巴西诺卡氏菌。这些抗生素对包括分枝杆菌属在内的革兰氏阳性菌有活性，但对革兰氏阴性菌或真菌无活性。它们对多重耐药的P388/ADR肿瘤细胞也有活性。
