Witte A M, Kool L J, Veenendaal R, Lamers C B, van Hoek B
Department of Gastroenterology, University Hospital Leiden, The Netherlands.
Am J Gastroenterol. 1997 Mar;92(3):498-501.
This report describes two patients with Budd-Chiari syndrome with intractable ascites due to a tight hepatic vein stenosis while the other hepatic veins were occluded. Percutaneous transluminal angioplasty of the hepatic vein stenosis followed by insertion of expandable metallic stents reduced the pressure gradient across the stenosis to almost zero. In both patients, ascites disappeared and diuretic therapy could be reduced significantly. This treatment has remained effective for more than 1 yr in one case and 2 yr in the other. These cases demonstrate the feasibility of hepatic vein stenting as a therapy for hepatic venous outflow obstruction. This therapy may be used in selected patients to defer and perhaps avoid shunt-surgery or liver transplantation.
本报告描述了两名布加综合征患者，他们因肝静脉严重狭窄且其他肝静脉闭塞而出现顽固性腹水。对肝静脉狭窄进行经皮腔内血管成形术，随后植入可扩张金属支架，使狭窄两端的压力梯度降至几乎为零。两名患者的腹水均消失，利尿剂治疗可显著减少。该治疗在一例患者中已持续有效超过1年，另一例超过2年。这些病例证明了肝静脉支架置入术作为肝静脉流出道梗阻治疗方法的可行性。这种治疗方法可用于特定患者，以推迟甚至避免分流手术或肝移植。
