Delint P J, Berendschot T T, van Norren D
Helmholtz Institute, Department of Ophthalmology, Utrecht University, The Netherlands.
Vision Res. 1997 Jan;37(2):243-8. doi: 10.1016/s0042-6989(96)00118-6.
The aim of this study was to develop a fast test for local photoreceptor alignment. Photoreceptor alignment is an important indicator of retinal integrity. Digitized images of fundus reflectance were obtained for 20-30 pupil entry positions with a custom built scanning laser ophthalmoscope (SLO). The data permitted the calculation of curve peakedness of the optical Stiles-Crawford effect (SCE) as a function of retinal location. We found that the peakedness is low in the central 0.5 deg, reaches a maximum at an eccentricity of 1-2 deg and gradually drops with increasing eccentricity. These data are in conformity with the anatomy of foveal cones. Additionally, the psychophysical SCE was measured with red light and an 8 deg stimulus. The mean peak position of the SCE in the pupil plane for both methods was similar, but the optical SCE was clearly steeper. The SLO provides a fast, reliable and objective way to determine local receptor alignment in the central retina.
