Taunay A E, Fernandes S A, Tavechio A T, Neves B C, Dias A M, Irino K
Instituto Adolfo Lutz, Seção de Bacteriologia, São Paulo, Brasil.
Rev Inst Med Trop Sao Paulo. 1996 Mar-Apr;38(2):119-27. doi: 10.1590/s0036-46651996000200006.
From 1950 to 1990 a total of 45,862 strains (31,517 isolates from human sources, and 14,345 of non-human origin) were identified at Instituto Adolfo Lutz. No prevalence of any serovars was seen during the period 1950-66 among human sources isolates. Important changing pattern was seen in 1968, when S. Typhimurium surprisingly increased becoming the prevalent serovar in the following decades. During the period of 1970-76, S. Typhimurium represented 77.7% of all serovar of human origin. Significant rise in S. Agona isolation as well as in the number of different serovars among human sources strains were seen in the late 70' and the 80's. More than one hundred different serovars were identified among non-human origin strains. Among serovars isolated from human sources, 74.9%, 15.5%, and 3.7% were recovered from stool, blood, and cerebrospinal fluid cultures, respectively. The outbreak of meningitis by S. Grumpensis in the 60's, emphasizes the concept that any Salmonella serovars can be a cause of epidemics, mainly of the nosocomial origin. This evaluation covering a long period shows the important role of the Public Health Laboratory in the surveillance of salmonellosis, one of the most frequent zoonosis in the world.
1950年至1990年期间，阿道夫·卢茨研究所共鉴定出45862株菌株（31517株分离自人类样本，14345株来自非人类来源）。1950年至1966年期间，在人类来源的分离株中未发现任何血清型的流行情况。1968年出现了重要的变化模式，当时鼠伤寒沙门氏菌出人意料地增加，在接下来的几十年里成为主要流行血清型。在1970年至1976年期间，鼠伤寒沙门氏菌占所有人类来源血清型的77.7%。20世纪70年代末和80年代，阿哥纳沙门氏菌的分离率以及人类来源菌株中不同血清型的数量显著上升。在非人类来源的菌株中鉴定出了一百多种不同的血清型。在从人类来源分离出的血清型中，分别有74.9%、15.5%和3.7%从粪便、血液和脑脊液培养物中分离得到。20世纪60年代格鲁姆彭西斯沙门氏菌引起的脑膜炎暴发，强调了任何沙门氏菌血清型都可能是疫情的起因，主要是医院源性疫情这一概念。这一涵盖长时间的评估显示了公共卫生实验室在监测沙门氏菌病（世界上最常见的人畜共患病之一）方面的重要作用。
