National Food Institute, WHO Collaborating Centre for Antimicrobial Resistance in Foodborne Pathogens and Community Reference Laboratory for Antimicrobial Resistance, Technical University of Denmark, Copenhagen, Denmark.
Foodborne Pathog Dis. 2011 Aug;8(8):887-900. doi: 10.1089/fpd.2010.0787. Epub 2011 Apr 14.
Salmonella enterica is commonly acquired from contaminated food and is an important cause of illness worldwide. Interventions are needed to control Salmonella; subtyping Salmonella by serotyping is useful for targeting such interventions. We, therefore, analyzed the global distribution of the 15 most frequently identified serovars of Salmonella isolated from humans from 2001 to 2007 in laboratories from 37 countries that participated in World Health Organization Global Foodborne Infections Network and demonstrated serotyping proficiency in the Global Foodborne Infections Network External Quality Assurance System. In all regions throughout the study period, with the exception of the Oceania and North American regions, Salmonella serovars Enteritidis and Typhimurium ranked as the most common and second most common serovar, respectively. In the North American and Oceania (Australia and New Zealand) regions, Salmonella serovar Typhimurium was the most common serovar reported, and Salmonella serovar Enteritidis was the second most common serovar. During the study period, the proportion of Salmonella isolates reported from humans that were Salmonella serovar Enteritidis was 43.5% (range: 40.6% [2007] to 44.9% [2003]), and Salmonella serovar Typhimurium was 17.1% (range: 15% [2007] to 18.9% [2001]). Salmonella serovars Newport (mainly observed in Latin and North American and European countries), Infantis (dominating in all regions), Virchow (mainly observed in Asian, European, and Oceanic countries), Hadar (profound in European countries), and Agona (intense in Latin and North American and European countries) were also frequently isolated with an overall proportion of 3.5%, 1.8%, 1.5%, 1.5%, and 0.8%, respectively. There were large differences in the most commonly isolated serovars between regions, but lesser differences between countries within the same region. The results also highlight the complexity of the global epidemiology of Salmonella and the need and importance for improving monitoring data of those serovars of highest epidemiologic importance.
肠炎沙门氏菌通常通过受污染的食物获得，是全世界发病的重要原因。需要采取干预措施来控制沙门氏菌；通过血清分型对沙门氏菌进行分型对于实施此类干预措施很有用。因此，我们分析了 2001 年至 2007 年期间，来自 37 个国家的实验室从人类中分离出的 15 种最常见血清型的肠炎沙门氏菌的全球分布情况，这些实验室参与了世界卫生组织全球食源性传染病网络，并在全球食源性传染病网络外部质量保证体系中证明了血清分型能力。在整个研究期间，除了大洋洲和北美地区外，在所有地区，肠炎沙门氏菌血清型肠炎和鼠伤寒血清型分别是最常见和第二常见的血清型。在北美和大洋洲（澳大利亚和新西兰）地区，鼠伤寒血清型报告的血清型最常见，肠炎血清型是第二常见的血清型。在研究期间，从人类报告的沙门氏菌分离株中，肠炎沙门氏菌血清型的比例为 43.5%（范围：40.6%[2007]至 44.9%[2003]），鼠伤寒血清型的比例为 17.1%（范围：15%[2007]至 18.9%[2001]）。纽波特血清型（主要在拉丁美洲和北美以及欧洲国家观察到）、婴儿血清型（在所有地区均占主导地位）、维尔肖血清型（主要在亚洲、欧洲和大洋洲国家观察到）、哈达血清型（在欧洲国家中较为普遍）和阿贡纳血清型（在拉丁美洲和北美以及欧洲国家中较为普遍）也经常被分离，其总体比例分别为 3.5%、1.8%、1.5%、1.5%和 0.8%。各地区最常分离的血清型之间存在很大差异，但同一地区的国家之间差异较小。结果还突出了沙门氏菌全球流行病学的复杂性，以及需要和重要性提高这些具有最高流行病学重要性的血清型监测数据。
