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雌性食蟹猴的社会压力、抑郁与脑多巴胺

Social stress, depression, and brain dopamine in female cynomolgus monkeys.

作者信息

Shively C A, Grant K A, Ehrenkaufer R L, Mach R H, Nader M A

机构信息

Department of Comparative Medicine, Physiology & Pharmacology, and Radiology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157, USA.

出版信息

Ann N Y Acad Sci. 1997 Jan 15;807:574-7. doi: 10.1111/j.1749-6632.1997.tb51972.x.

Abstract

Socially subordinate adult female cynomolgus monkeys are hypercortisolemic, the targets of aggression, fearful, vigilant, receive little positive affiliative contact, exhibit pathological behaviors indicating anxiety, and are disengaged in the social events around them. Subordinates also have altered dopaminergic activity that may be due to decreased D2 receptor binding. Dopaminergic activity indices were more closely associated with affiliative than agonistic behaviors.

摘要

社会地位较低的成年雌性食蟹猴皮质醇水平过高,是攻击行为的目标对象,恐惧、警惕,很少有积极的亲和接触,表现出表明焦虑的病理行为,并且对周围的社交活动不参与。从属食蟹猴的多巴胺能活动也发生了改变,这可能是由于D2受体结合减少所致。多巴胺能活动指标与亲和行为的关联比与攻击行为的关联更为密切。

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