Betney S, Morgan P B, Doyle S J, Efron N
Department of Optometry and Vision Sciences, University of Manchester Institute of Science and Technology, England.
Cornea. 1997 Mar;16(2):158-61.
Corneal temperature changes in photorefractive keratectomy (PRK) have been implicated in the aetiology of subepithelial haze. This study was undertaken to quantify the temperature change during this surgical procedure.
Non-contact, colour-coded ocular thermography was performed by using an infrared detection system during PRK on a group of 12 subjects.
Mean (+/-SD) central ocular surface temperature (OST) after epithelial debridement was 29.15 +/- 0.39 degrees C. Mean peak OST during PRK was 37.77 +/- 0.67 degrees C, with most of the temperature increase occurring during the first 15 s. Factors such as ablation depth, optical correction, and procedure duration were not demonstrated to have a significant effect on corneal temperature during the procedure, suggesting a complex relation between-PRK parameters and the change in corneal temperature.
Previous work suggested that corneal collagen denatures at approximately 39 degrees C, and it has been demonstrated that corneal temperature may be elevated to this level during routine PRK. Further research is indicated into the effects of preoperative cooling and pausing in treatment to reduce temperature changes.
准分子激光角膜切削术(PRK)中角膜温度变化与上皮下雾状混浊的病因有关。本研究旨在量化该手术过程中的温度变化。
在一组12名受试者进行PRK手术期间,使用红外检测系统进行非接触式彩色编码眼热成像。
上皮清创术后平均(±标准差)中央眼表温度(OST)为29.15±0.39℃。PRK期间平均峰值OST为37.77±0.67℃,大部分温度升高发生在最初15秒内。消融深度、屈光矫正和手术持续时间等因素在手术过程中未显示对角膜温度有显著影响,提示PRK参数与角膜温度变化之间存在复杂关系。
先前的研究表明角膜胶原蛋白在约39℃时变性,并且已经证明在常规PRK期间角膜温度可能升高到这个水平。需要进一步研究术前冷却和治疗中暂停对减少温度变化的影响。