评估接受家庭肠外营养的肠衰竭患者的生活质量。
Assessing the quality of life of patients with intestinal failure on home parenteral nutrition.
作者信息
Richards D M, Irving M H
机构信息
University of Manchester Intestinal Failure Unit, Salford Royal Hospitals Trust.
出版信息
Gut. 1997 Feb;40(2):218-22. doi: 10.1136/gut.40.2.218.
BACKGROUND
A study was performed to measure the quality of life of patients receiving home parenteral nutrition (HPN). Quality of life is an important determinant of the effectiveness of health technologies, but it has rarely been assessed in patients receiving HPN.
AIMS
To measure quality of life and highlight any moderating factors.
PATIENTS AND METHODS
Quality of life was measured using two validated instruments (SF 36 and EuroQol) in 51 patients with intestinal failure. All patients had benign disease, the commonest being Crohn's disease (n = 35).
RESULTS
HPN patient scores were worse for six of eight SF 36 domains (p < 0.05) compared with standard population scores. Younger patients (< 45) had good scores but older patients (> 55 years) scored significantly less. Patients addicted to narcotic substances had very low scores. EuroQol utility scores confirmed the SF results. Forty one patients reported that they felt too ill to work and only five were in full time work or education.
CONCLUSIONS
The health status profile of our young patients on HPN was good compared with the normal population. The poorest scores were in older patients and those dependent on narcotic drugs. This has clinical and economic relevance when considering such patients for HPN.
背景
开展了一项研究以衡量接受家庭肠内营养（HPN）患者的生活质量。生活质量是健康技术有效性的一个重要决定因素，但在接受HPN的患者中很少对此进行评估。
目的
衡量生活质量并突出任何调节因素。
患者与方法
使用两种经过验证的工具（SF - 36和欧洲五维度健康量表）对51例肠衰竭患者的生活质量进行测量。所有患者均患有良性疾病，最常见的是克罗恩病（n = 35）。
结果
与标准人群评分相比，HPN患者在SF - 36八个维度中的六个维度得分更低（p < 0.05）。年轻患者（< 45岁）得分较好，但老年患者（> 55岁）得分显著更低。对麻醉药品成瘾的患者得分非常低。欧洲五维度健康量表效用评分证实了SF - 36的结果。41名患者报告称他们感觉病得太重无法工作，只有5人全职工作或接受教育。
结论
与正常人群相比，我们接受HPN的年轻患者的健康状况较好。得分最差的是老年患者和那些依赖麻醉药品的患者。在考虑为这类患者提供HPN时，这具有临床和经济意义。
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