Williams N, Carlson G L, Scott N A, Irving M H
Department of Surgery, University of Manchester, Hope Hospital, Salford, UK.
Br J Surg. 1994 Mar;81(3):392-4. doi: 10.1002/bjs.1800810324.
Fifty patients, comprising 24 male and 26 female of median age 43 (range 15-67) years, received a total of 2620 patient-months of home parenteral nutrition (median 48 (range 2-130) months). There were 13 episodes of bacterial catheter sepsis (of which the catheter was successfully salvaged by an antibiotic-fibrinolytic 'lock' technique in four cases) and ten of exit-site sepsis (all managed by elective catheter replacement), representing an incidence of 1 septic complication per 113 patient-months of parenteral nutrition. This low incidence of catheter-related sepsis was achieved by strict adherence to established protocols of catheter management.
50例患者（其中男性24例，女性26例，年龄中位数为43岁（范围15 - 67岁））共接受了2620个患者月的家庭肠外营养治疗（中位数为48个月（范围2 - 130个月））。发生了13例细菌性导管败血症（其中4例通过抗生素 - 纤维蛋白溶解“封管”技术成功挽救导管）和10例出口部位败血症（均通过选择性更换导管处理），即每113个患者月的肠外营养治疗发生1例感染并发症。通过严格遵守既定的导管管理方案，实现了导管相关败血症的低发生率。
